CDC National Center for Emerging and Zoonotic Infectious Diseases Objectives for the Centers of Excellence in Vector Borne Diseases (RFA-CK-17-005):
Building the capacity to address the problem of emerging and exotic vector-borne diseases in the U.S., including Zika virus infection. The specific goals of these centers are to: (1) conduct applied research to develop and validate effective VBD prevention and control tools and methods necessary to anticipate and respond to disease outbreaks; (2) train a cadre of public health entomologists with the knowledge and skills required to rapidly detect and respond to VBD threats in the United States; and (3) build effective collaborations between academic communities and public health organizations at federal, state, and local levels for VBD surveillance, prevention, and response. The ultimate objective (4) is for these centers to help generate the necessary knowledge and capacity to enable appropriate and timely local public health action for VBD to be taken throughout the U.S., given significant regional differences in vector ecology, disease transmission dynamics and resources.
The key, unique feature of our modeling framework is the focus of its design on efficient statistical inference, placing the key focus of the work on tying models to data. We will use these models to estimate the value of information obtained through specific surveillance activities in order to tune existing surveillance programs and refine study designs. We will also use this framework to determine the most efficient ways to measure the impact of control measures deployed in the State of Florida. This could serve as a template for other Southeast US mosquito/vector control programs to examine in terms of its relevance to their respective transmission context. The overall goal is to develop tools that can be used in the design of studies and surveillance by collaborators on this grant and more broadly by the larger community in the Southeast US.
The anticipated outcomes of our center include but are not limited to: