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Tick-Host-Pathogen Interactions at the Feeding Site National Institute of Allergy and Infectious Diseases, Rocky Mountain Labs, Hamilton, MT Position Description: The Tick-Pathogen Transmission Unit at Laboratory of Bacteriology (LB), Rocky Mountain Laboratories (RML), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Helath (NIH) is seeking to recruit an outstanding postdoctoral fellow to study tick-host-pathogen interaction at molecular and cellular level at the tick feeding site. For this project, next generation sequencing, proteomic analysis, and immunohistochemistry will be utilized to understand host immunomodulation induced by Borrelia burgdorferi-infected and non-infected I. scapularis nymphs during feeding in a mouse model. By studying interactions between the host immune response and tick-mediated immunomodulation during tick feeding, we can begin to understand the immunologic processes that facilitate transmission of Borrelia burgdorferi to a host. Findings of this study will be useful in constructing pathways through which ticks successfully feed and transmit pathogens, leading to the development of potential new pathogen blocking strategies. Through the Research Technologies Branch, our lab has access to state-of-the-art research technologies including flow cytometry, genomics, protein chemistry, structural biology, microscopy, among others. For additional information on the Research Technologies Branch, please visit: The Rocky Mountain Laboratories (RML) are located in Hamilton, Montana, a small but thriving community nestled between the Bitterroot and Sapphire Mountains. For additional information on the Rocky Mountain Laboratories, please visit: As a key component of the Division of Intramural Research, RML is perhaps best known for its research into vector-borne diseases, such as Rocky Mountain spotted fever, Q fever, and Lyme disease—three illnesses caused by microbes whose names pay tribute to the former RML scientists who discovered them. For additional information on the history of the Rocky Mountain Laboratories, please visit: In terms of scientific opportunities, the NIH is absolutely unique in bringing scientists from virtually all areas of biomedical sciences in one Institute. A program fostering scientific exchange and collaboration between NIAID laboratories in Hamilton and Bethesda/Rockville is available and the successful applicant will have opportunities to collaborate with these labs and groups. Visit NIAID Careers for more information about working in NIAID’s dynamic atmosphere. The salary and benefits are as per NIH regulations commensurate with experience. Qualifications: • Candidates must hold an M.D./Ph.D. or Ph.D. in a cognate field, within five years of degree being awarded; • Preference will be given to candidates with a strong background in molecular biology, proteomics and/or immunology; • A strong training in molecular biology/immunology with experience in transcriptomics and/or proteomic analysis, animal handling is desired; • Prior experience working with ticks and/or Borrelia burgdorferi will be an added advantage; • We are looking for candidates with excellent writing and communication skills; • We are a small, friendly lab and ability to work both independently and with other members as part of a cohesive group is important. To Apply: Applicants should send a short statement of research goals, curriculum vitae, bibliography, and names and contact information of three references to Dr. Lucas Tirloni ( Selected candidates will be invited for an online interview. Tentative starting date: June 2020. Underrepresented minorities are especially encouraged to apply. NIH is dedicated to building a diverse community in its training and employment programs. HHS, NIH, and NIAID are equal opportunity employers

Agency SUNY-ESF Location Syracuse, NY Job Category Graduate Assistantships

Salary ~22,000/year

Start Date 07/01/2020

Last Date to Apply 08/31/2020 Website Description The Tick and Tick-Borne Disease Lab (Leydet lab: at the State University of New York College of Environmental Science and Forestry (ESF) is seeking PhD applicants for a field/laboratory research project seeking to understand impacts of landscape on tick and tick-borne disease ecology. The successful applicant will have significant flexibility in the specifics of their project but will be expected to work closely with the Downs Lab ( on this collaborative project. Generally, the student will employ fieldwork, use molecular tools, and spatial/ecological statistics to delineate ecological factors influencing ticks and their diseases. We expect the applicant will also work closely other faculty at ESF studying especially animal physiology of hosts, ecoimmunology, habitat/land management, and conservation.

Terms of the Position: We are seeking an applicant to begin Summer/August 2020. The student will be supported by a combination of research and teaching assistantships (~22,000/year plus full tuition waiver and benefits including medical, dental, and vision).

Application Deadline: Applications will be accepted until the position is filled.

Send the following to CV, statement of research goals, copy of transcripts, copy of GRE scores. Documents should be submitted as a single PDF named: tick.pdf (e.g., Leydet_tick.pdf). The email should contain the subject line “Tick Ecology”. SUNY-ESF is an equal opportunity, equal access academic institution that embraces diversity and inclusion in the workplace.

Qualifications: Ideal candidates will have a Master’s degree with an interest in vector-borne diseases (exceptional candidates with an undergraduate degree will also be considered). The applicant should be experience in concepts of community/landscape ecology and animal physiology. Strong organization, quantitative, and communication skills and a valid driver’s license are required.

Preferred Qualifications: Experience in molecular biology lab work, including PCR, DNA sequencing, and sequence analysis. Experience with small mammal trapping and handling. Experience with managing large data sets, spatial statistic, and Program R. A strong record of academic and research achievements. Competitive applicants typically have a GPA 3.5 or higher and GRE scores above average in all categories with 2 of the 3 scores > 75th percentile, prior publications or manuscripts in review preferred.

Contact: Brian Leydet

The Southeastern Regional Center of Excellence in Vector Borne Diseases is supported through a cooperative agreement between the Centers for Disease Control and Prevention (CDC) and the University of Florida.


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