Long Tag 4

The Four Pillar Universities of the Gateway Program

This is a unified, flagship program from the State of Florida, led by the University of Florida, Florida International University, the University of Miami and the University of South Florida to establish a Regional Center of Excellence in Vector Borne Disease (VBD) in the Southeastern US, with the following objectives: (1) develop novel control interventions and discover insecticide-resistance-breaking compounds; (2) expand  the level of inter-institute/inter-agency coordination and partnership in the exchange of research and operational information in the Southeast; (3) establish a compreh

PROJECT 4 | Multi-scale, modular models for Vector-Borne Disease

Background | Models of arbovirus transmission are useful in estimating the burden of Dengue, forecasting areas of risk for the emergence of Dengue, Chikungunya and Zika in non-endemic areas, and in assessing the potential of control interventions. The utility of these models relies on their grounding in empirical data at multiple scales describing the disease transmission process. The aims are to (i) model the dynamics of viruses in their invertebrate and vertebrate hosts as well as the movement of these hosts viz.

PROJECT 2 | Breaking the transmission of zoonotic arboviruses by mosquitoes

Background | Eastern Equine Encephalitis virus (EEEV) can over-winter in ectothermic hosts. The overall aim of this project is to predict at the focal level where over-wintering is occurring in Florida, and to leverage complementary mathematical models (Project 4) to develop early season intervention strategies to interrupt wintertime EEEV transmission.  We hypothesize that such early season interventions will lessen or prevent outbreaks of EEEV later in the year, when mosquito densities are greater and the costs for intervention correspondingly higher.  

 

PROJECT 1 | Understanding vector ecology, arbovirus infectious rates & insecticide resistance to optimize mosquito control

The biocomplexity of Aedes vectors of Zika, Dengue, Chikungunya, and other arboviruses in the US remains understudied. We will investigate how fundamental, field-based information on the complexities of vector ecology and adaptation can be used to parameterize local and global models (Project 4) for predicting disease transmission and forecasting the longer-term potential of novel vector control tools in effecting optimized vector control in urban environments. ​